Advanced ovarian cancer data

Data from two clinical trials comparing combination chemotherapies for advanced ovarian cancer (Neijt et al. 1984, 1987). The data were originally distributed in the archived dynpred package (as ova).

Usage

data(ova)

Format

A data frame with 358 rows, one per patient:

tyears

numeric: time in years until death or last follow-up.

d

survival status; 1 = death, 0 = censored.

Karn

numeric: Karnofsky score, recoded from 6 (\(\le 60\)) to 10 (100).

Broders

factor: Broders' histological grade, with levels "1", "2", "3", "4", "unknown".

FIGO

factor: FIGO stage, with levels "III" and "IV".

Ascites

factor: presence of ascites, with levels "absent", "present", "unknown".

Diam

factor: diameter of the residual tumour, with levels "micr.", "<1cm", "1-2cm", "2-5cm", ">5cm".

id

integer: patient identifier.

Source

The archived dynpred package (GPL (>= 2)), companion to van Houwelingen & Putter (2012).

References

van Houwelingen HC, Putter H (2012). Dynamic Prediction in Clinical Survival Analysis. Chapman & Hall.

Neijt JP, ten Bokkel Huinink WW, van der Burg MEL, et al. Randomised trial comparing two combination chemotherapy regimens (Hexa-CAF vs CHAP-5) in advanced ovarian carcinoma. Lancet. 1984; 2: 594-600.

Neijt JP, ten Bokkel Huinink WW, van der Burg MEL, et al. Randomized trial comparing two combination chemotherapy regimens (CHAP-5 vs CP) in advanced ovarian carcinoma. J Clin Oncol. 1987; 5: 1157-1168.